Abstract

DETECTION AND ESTIMATION OF FLAVONOIDS, PHENOLIC ACIDS AND XANTHONE IN CLERODENDRUM SERRATUM ROOT AND PREMNA HERBACEAE ROOT EXTRACTS BY HPTLC TECHNIQUE

Dibesh S., Kabilan T., Hema Chandran V., Jahan R., Dhanus C. T. R., Arivukkarasu R.* and Rajasekaran A.

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Abstract

The prime aim of the study is to observe the flavonoids, phenolic acids and xanthone in two herbal raw materials clerodendrum serratum root and Premna herbaceae root from verbanaceae family. Traditional siddha practitioners instead of clerodendrum serratum root using Premna herbaceae root as substitute in herbal formulations because both are belongs to Verbenaceae and used for similar symptoms of disease. Our aim of interest to detect and estimate antioxidatant markers in clerodendrum serratum root and Premna herbaceae root. Results of the study clearly revealed that clerodendrum serratum root reveals caffeic acid and rutin but premna herbaceae root exhibits only caffeic acid. Rutin and caffeic acid was found to be 0.04 and & 0.27% respectively in clerodendrumserratum root. Caffeic acid was found to be 5.536% in Premnaherbaceae root. In Conclusion the antioxidant markercaffeic acid were present in both extracts but Premna herbaceae root extracts only caffeic acid. The clerodendrum serratum literature reveals anti-inflammatory, antioxidant, antibacterial, hepatoprotective and anticancer and Premna herbacea possess antipyretic, antiinflammatory and anti nociseptic activity may be due to presence of antioxidant markers like caffeic acid and rutin present in the extracts.

Keywords: Caffeic acid, Gallic acid, HPTLC, Mangiferin, Rutin, Quercetin.