Abstract

INNOVATIVE ASPECTS OF SYMBIOTIC LECTINS AND THEIR RECOGNIZED GLYCOCONJUGATES

Vladimir M. Lakhtin*, Mikhail V. Lakhtin and Vladimir A. Aleshkin

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Abstract

Own results are summarized. Innovation potential of symbiotic/ probiotics lectins (SPLs) is described. SPLs function as systems. Systems of SPLs recognize, reversibly bind, deliver, fix and orient on cell surface polymeric polyvalent glycoconjugates (GC) imitating natural carbohydrates-containing compounds. SPLs imitate pro/sym/synbiotics, don’t depend on the presence of antimicrobials (synergistic to them), act as multitarget communicative metabolomebiotics (network-to/in-network), cofunction to enzymes, inhibit virulent factors of pathogens, reveal antifungal and antistaphylococcal activities, directed against communicative massifs of pathogens, organize and support GC-décor of mucosal organs of organism open cavities, participate in delivery of GC-type prebiotics and probiotics, metabiotics, antibiotics and other therapeutics. The potential of the components and their systems of the symbiotic/probiotic compartment of the mucosal biotope is presented as innovations and for innovations, including when considering technologies such as metabolic, cellular-metabolic, other biological and therapeutically significant. It is proposed to identify the communication potential of any protein mixtures using specific GC sets. Ways of obtaining complex biological products of new types have been discovered. The results are of interest for innovations in cell biology, mucosal immunity, pro/pre/synbiotic prevention and therapy, infectology, prognostic diagnostic and (nano)biotechnological medicine.

Keywords: symbiotic lectins; probiotics; glycoconjugates; antimicrobials; microbiocenoses; mucosal immunity.