Abstract

PHARMACEUTICO- ANALYTICAL STUDY OF RAKTA STHAPANA CHURNA

B. S. Kasturirangan*, Angadi Ravindra, B. N. Ashok Kumar and R. R. Geethesh

.

Abstract

Rakta Sthapana Churna is an Ayurvedic formulation designed for external application during Rakta Mokshana to address atipravarthana or bleeding tendencies. The research aims to evaluate the pharmaceutical and analytical aspects of this formulation, considering its potential applications in haemorrhagic disorders. Aims & Objectives: The primary aim of this study is to conduct pharmaceutical and analytical studies on Rakta Sthapana churna, a compound formulation for modulating the blood flow. Materials & Methods: The pharmaceutical study involves preparation of churnas of all the herbal ingredients, Gairika shodhana, Kanji preparation, shankha-shukti shodhana and its churna preparation, preparation of Rasanjana, and finally the compound churna preparation. The analytical study comprises organoleptic, physicochemical, and chromatographic evaluations. Results: The preparation of Rakta Sthapana Churna involved continuous trituration, resulting in a light brown coloured churna with an odour predominantly of Sarjarasa, Rasanjana & Godhuma, possessing Madhura-kashaya-tikta rasa. The quantity obtained was 650g. Analytical parameters and HPTLC provided relatable results. Discussion: The pharmaceutical study involves size reduction and separation principles. Gairika shodhana highlights the importance of selecting appropriate shodhana method. Shankha churna preparation explores commentary-based insights in Ayurvedic pharmaceutics. Organoleptic evaluation shows kashaya rasa, associated with sthambhana property, along with guru guna of madhura rasa, which could contribute to the rakta sthapana or blood-stabilizing effect. HPTLC demonstrates distinct compound patterns. Conclusion: The study offers the standardization of Rakta Sthapana Churna & provides a foundation for further research in the field of Ayurvedic preparations pertaining to haemostasis.

Keywords: Rakta sthapana, atipravarthana, haemorrhagic disorders, pharmaceutical, analytical, standardization.