Abstract

FORMULATION AND EVALUATION OF HERBAL OINTMENT OF ETHANOLIC EXTRACT OF ACALYPHA INDICA LINN.

*M. Sakthivel, *M. Mohamed Halith, K. Siva, R. Sivaguru, R. Sivasankari, R. Srikanth and L. Sriram

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Abstract

Acalypha indica is an important Indian medicinal plant and widely used in Ayurveda and siddha for management of various disease. Previous studies reported the activity of analgesic, anti-inflammatory, anti-bacterial, anti-viral ana anti-fungal properties of acalypha indica. The present study investigated the potential wound healing activity of ethanol leaf extract o acalypha indica L topical formulation. Fresh plant samples were extracted via a maceration in increasing polarity using petroleum ether, chloroform and methanol. Hence a study was conducted to formulate wound healing ointment containing methanolic extract of acalypha indica and showing effective antibacterial activity. Several researches revealed the antibacterial, antioxidant and antiinflammatory properties of these plant. Extracts and chemical constituents of this plant possess useful pharmacological activities. The main pharmacological activity of acalypha indica is wound healing property. These results suggest that ointment of ethanol leaf extract of acalypha indica could be an answer to facilitate wound healing, to approve the traditional claims of the plant in wound healing activity.

Keywords: Acalypha indica, ethanolic extract, ointment base, wound healing property.