Abstract

A RANDOMISED CONTROLLED CLINICAL STUDY TO EVALUATE EFFICACY OF SAPTACHAKRA CHURNA (SALACIA RETICULATA) IN MADHUMEHA W.S.R TYPE-2 DM

Javeed Chougala*, Surekha Pai and Babu Paul

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Abstract

Background: Madhumeha is one among the Ashta Mahagadas,[1] It explained as one of the Vata pradhana tridoshaja vyadi.[2,3] Acc. to Sushruta these are 2 types, Pathophysiologically its Dhatu kshayaja and Avarnaja.[2] This Madhumeha is corelates with the Diabetes Mellitus in modern science, Diabetes is the metabolic disorder associated with hyperglycemia. If not controlled in time leads to end stage renal disease.[4] India is expected to be the ‘World Diabetes capital’ because India has genetic predisposition to develop Diabetes mellitus which is further precipitated by life style.[4] This study focuses on comparative effect of the Saptachakra churna and Amalaki churna in Madhumeha w.s.r to Type – 2 Diabetes mellitus. Saptachakra is the drug which explained by Vaidhya Priyavat Sharma[5] and in Phalashruti its exclusively indicated for Madhumeha and Yakrut rogas.[5,6,7] Materials and Methods: A randomised controlled clinical study was conducted among 60 subjects, they were randomly allocated into two equal groups, Group A subjects received Saptachakra churna and Group B subjects received Amalaki Churna. Effect of these intervention assessed through subjective and objective parameters. Result & Conclusion: Both groups shown highly statistical significant with P < 0.001 for the objective parameters. When we compare both groups, it shown that there is statistical significant difference between Saptachakra churna and Amalaki churna in Madhumeha w.s.r. type 2 Diabetes Mellitus.

Keywords: Diabetes mellitus, Madhumeha, Saptachakra churna, Amalaki Churna and Beta-sitosterol.