Abstract

A REVIEW ON OCUULAR DRUG DELIVERY

Mr. Arpit Gawshinde*, Dr. Dharmendra Solanki, Mr. Umesh K. Atneriya, Dr. Rekha Gour, Mrs. Pushpanjali Chaursia, Ms. Vaishali Kori

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Abstract

Ocular drug delivery is maintenance of an adequate concentration of drug in the pre-corneal area. Ocular administration of the drug is primarily associated with the need to treat ophthalmic diseases. Topical application of drugs to the eye is the well-established routes of administration for the treatment of various eye diseases like dryness, conjunctiva, and eye flu etc. Conventional topical ocular delivery systems include various dosage forms such as solutions, suspensions, emulsions, ointments, gels, erodible inserts, non-erodible inserts which shows drawbacks such as rapid pre-corneal elimination, blurred vision, abrasion, irritation to eye, tissue fibrosis, matted eyelids after use and patient discomfort etc. In order to overcome these, vesicular system for drug delivery are used such as Liposomes Niosomes, Pharmacosomes and discomes. Various ocular drug delivery devices are used that can deliver drug to eye such as Matrix-type drug delivery systems, Capsular type drug delivery systems, Implantable drug delivery pumps etc .The field of ocular delivery is one of the most interesting and challenging Endeavours facing the pharmaceutical scientist.

Keywords: Ocuular Drug Delivery System, Anatomy and Physiology of Eye, Conjunctivitis.