Abstract

DETECTION AND ESTIMATION OF RUTIN, QUERCETIN, GALLIC ACID, CATECHIN, ELLAGIC ACID AND FERULIC ACID IN HERBAL RAW MATERIALS AVAILABLE IN MARKET TO TREAT VIRAL PATHOGENS SARS-COV-2 BELONGS TO PHYLLANTHUS & FICUS SPECIES BY HPTLC TECHNIQUE

Mukil M., Sabitha S., Naresh Kumar S., Rajasekaran A. and Arivukkarasu R.*

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Abstract

The prime aim of the study is to detect and estimate the flavonoids, and phenolic acids in five commercial herbal raw materials namely Phyllanthus Emblica dry fruit, Phyllanthus pinnatus entire herb, Ficus bengalensis bark, Ficus religiosa bark, Ficus racemosa bark obtained from Phyllanthus and Ficus species used in treatment for SARS-CoV- 2 infection. We plan to confirm the presence of mentioned common secondary metabolites in herbal raw materials. Results of the study clearly revealed that these raw materials from Phyllanthus and Ficus species contains flavonoids and phenolic acids. The developed HPTLC method can be employed for the routine investigations of flavonoids and phenolic acids in herbal raw materials. Phyllanthus Emblica dry fruit, Phyllanthus pinnatus entire herb and Ficus racemosa bark was ascertain the presence of Ellagic acid and be evidence for the 0.80%, 0.68% and 0.02% respectively. Gallic acid was estimated in Phyllanthus Emblica dry fruit, bengalensis bark, Ficus religiosa bark as 0.54%, 0.03% and 0.09% respectively. Quercetin was predictable in all five herbal extracts Phyllanthus Emblica, Phyllanthus pinnatus, Ficus bengalensis, Ficus religiosa, Ficus racemosa 0.03%, 0.05%, and 0.12%, 0.12% and 0.27% respectively.

Keywords: Ellagic acid, Quercetin, Gallic acid, Rutin HPTLC.