Abstract

AJWAIN [TRACHYSPERMUM AMMI (LINN.)]: AN EVIDENCE-BASED REVIEW ON ITS PHYTOCHEMICAL ASPECT, ETHNOPHARMACOLOGY, THERAPEUTIC POTENTIAL AND ITS DERMATOLOGICAL BENEFITS

Ayman Danish Kirmani*, Abdul Wahab, Mohammad Aslam, Rasikh Javed, Aisha Siddiqui, Faiza Mukhtar

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Abstract

Background: The Umbelliferae family, which includes the wellknown Unani plant Ajwain, is found in tropical Africa, the Mediterranean region, South-West Asian countries, India, and West China. Ajwain has long been used in Unani medicine to treat conditions related to the digestive system, the respiratory system, neurological illnesses, hepatic and genitourinary disorders. Using a variety of electronic databases, including as Pub Med, Web of Science, Science Direct, Elsevier, Google Scholar, and others, a thorough review of the literature on Ajwain has been done. Books like Azam Khan's Muheet e Azam, Khazainul Advia of Najmul Ghani, Hakim Abdul Hakeem's Bustanul Mufradat, Hakim Kabeer-ud-din's Ikseere Azam, and Abu Alhassan Ali Ibne-e Abbas's Kamil Sanaa were also consulted. Using the Glossary of Indian Medicinal Plants and a number of indexed publications, a comprehensive analysis of the botanical and English names of medicinal plants was carried out (Chopra et al., 1956). The results showed that the plant possesses a wide range of pharmacological properties, including digestive, anti-cancer, anti-inflammatory, antifungal, anti-bacterial, and estrogenic effects. These properties are likely caused by the presence of aromatic compounds like thymol, carvone, limonene, dillapiole, hygroscopic saponin, and crystalline flavone. Because of its many pharmacological qualities and significance to human health, Trachyspermum ammi is potentially useful in the creation of a variety of drugs.

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