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Abstract

A RETROSPECTIVE OBSERVATIONAL STUDY ON EVALUATION OF USE OF ANTIBIOTICS WITH THEIR RESISTANCE IN PATIENTS WITH LRTI’s

R. Arjun Singh*, Sobia Khan, Mohammed Adil, Salman Ahmed Khan and Dr. A. V. Kishore Babu

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Abstract

A Retrospective Observational study was carried out to evaluate the use of antibiotic therapy and co-relating it with antibiotic resistance in patients with Lower Respiratory Tract Infections (LRTIs) who were presented to Olive Hospitals during January 2022 - January 2023. Total of 200 patients, which includes both men and women, those who satisfy the inclusion criteria were selected, among which 57% were female patients and rest 43% were male. The age-group ranging between 50- 60years have greater number of patients (44 patients) followed by 60- 70 years with 38 patients suffering with LRTIs. It was noticed that most of the patients with LRTIs taken under the study does not have any social addictions i.e., 63.50% have no addictions followed by 15% of patients were found to be smokers (especially male patients) and it was observed that 78% (157 patients) of the patients have comorbidity conditions. Out of 200 patients, (88) patients were diagnosed with “PNEUMONIA” followed by (32) patients diagnosed with Chronic obstructive pulmonary disease (COPD). (24) patients (12%) were found to be drug resistant to antibiotics out of which (19) patients were resistance to Cephalosporin class of antibiotics. During the course of treatment, one or more antibiotics was prescribed by the physician to the patients based on patient’s clinical condition. It was observed that “CEPHALOSPORIN” class of antibiotics was advised for majority of the patients, 147 patients were treated with Cephalosporins alone or in combination with other antibiotics and those who were resistance to Cephalosporins were treated with “Macrolide Antibiotics”.

Keywords: Lower respiratory tract infections (LRTIs), Pneumonia, Cephalosporins, Antibiotics, Drug-resistance, Macrolide Antibiotics.


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