Abstract

EVALUATION OF ANTICONVULSANT ACTIVITY OF LEAVES EXTRACTS OF PASSIFLORA INCARNATA AND LAWSONIA INERMIS IN RAT MODEL

Shaik Abdul Nadim* and Rubeeya N. Lodhi

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Abstract

Epilepsy is a chronic no communicable disorder of the brain, occurs all over in all areas of the world and not less than three out of every thousand people – and in several places over 40 per thousand (4%) – are affected. Every year, among every 100, 000 persons there will be a 40 – 70 new cases recorded. Epilepsy is a disorder of the brain in which the patient is prone to get epileptic "seizures" or "fits", and persons having two or more unprovoked fits or seizures can be said to have Epilepsy. As per the WHO, epilepsy is the commonest serious disorder of the brain, and epileptic fit or seizure is caused by brief, excessive and abnormal discharge of nerve cells in the brain, like a small "electrical storm" or "short circuiting" in the brain.

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