Abstract

IMPACT OF ANTIMICROBIAL STEWARDSHIP IN SURGICAL SITE INFECTIONS

*Dr. Fabin, Mahesh Waghchaure, Dr. Rahul Kamble, Punya Prakash and Dr. Prajakta Pawar

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Abstract

Surgical site infections (SSIs) are the most common health care associated infections. The appropriate use of Surgical Antibiotic Prophylaxis (SAP) is a key component to reduce SSIs, while its inappropriate application is a major cause of some emerging infections and selects for antibiotic resistance. We describe an Antimicrobial Stewardship (AMS) intervention on SAP appropriateness because “Antimicrobial stewardship programs (ASPs) have become a fundamental pillar in optimizing antimicrobial usage, improving patient care, and reducing antimicrobial resistance (AMR). The prospective Observational study was conducted in Narayani hospital, nashik in surgical units by implementing hospital evidence-based guidelines and a new workflow to optimize the process of administering and documenting the SAP. We analyzed 2662 surgical cases from Jun 2022 to April 2023 for 2 SAP parameters of appropriateness: choice and timing and an audit was performed every month to analyze the results. The analysis and audit demonstrated that most of the surgical patients received antibiotics and the most prescribed antibiotics were cefuroxim (62%) and Ceftriaxone (21%) and a significant improvement of appropriate choice (72-100%), surgical prophylaxis compliance (86-100%) and rate of SSI also reduced. Our study demonstrates a model of successful antimicrobial stewardship intervention that improves appropriateness on SAP.

Keywords: Surgical site infections (SSIs), Surgical Antibiotic Prophylaxis (SAP), Antimicrobial Stewardship (AMS).