Abstract

“PHYTOCHEMICAL SCREENING AND INVITRO ANTHELMINTIC ACTIVITY OF METHANOLIC EXTRACT OF CARICA PAPAYA LEAVES”

L. Krishnaveni*, Dr. J. Kumar Raja, D. Thasri Sharmaji, G. Soumya, J. Nandhini, M. Sowmya, N. Syam Prakash and P. Sri Ragavi

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Abstract

Development of anthelmintic resistance and high cost of conventional anthelmintic drugs lead to the evaluation of medicinal plants as an alternative source of anthelmintics. In the present study, the leaves of carica papaya were successively extracted with maceration using methanol as a solvent. The aim of the present study was to perform the phytochemical screening and to evaluate the anthelmintic activity of methanolic extract of leaves of carica papaya belonging to the family caricaceae. The anthelmintic activity was analyzed by methanolic extract of different concentrations-25,50,100mg/ml by using Indian adult earthworm, Pheretima posthuma having anatomical and physiological look like with the intestinal worms.The time of paralysis and the time of death were studied and the activity was compared with Piperazine citrate as a standad reference. We demonstrated that, the results supported the traditional use of carica papaya in the treatment of Helminthiasis.

Keywords: Carica papaya, phytochemical screening, pheretima posthuma, piperazine citrate.