Abstract

ANTIULCER EFFECT OF MIRABILIS JALAPA BY USING DIFFERENT PARADIGMS ON RAT MODELS

Vinjavarapu L. Anusha*, B. Venkata Lakshmi, A. Vyshnavi, E. Vinay Rakshan Kumar, S. K. Raquieb, M. Pawan Kumar and Dr. B. Thangabalan

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Abstract

In this narrative review, we have comprehensively reviewed the plant sources used as antiulcer agents. From traditional uses as herbal remedies, we have moved on to preclinical evidence, critically discussing the in vitro and in vivo studies focusing on plant extracts and even isolated phytochemicals with antiulcerogenic potential. A particular emphasis was also paid to mirabilis jalapa activity, with emphasis on involved mechanisms of action. Lastly, the issue of safety profile of these plant products has also been addressed.

Keywords: Antiulcer agents, preclinical evidence, mirabilis jalapa etc.