Abstract

A REVIEW OF ITS PHYTOCHEMISTRY AND PHARMACOLOGY: ARTOCARPUS HIRSUTUS

*S. Shervinjose and K. V. Vinothini

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Abstract

The Artocarpus hirsutus is a member of the Moraceae family, which includes around 50 species. It has historically been used to treat diseases of the skin, snake bites, diarrhoea, joint pain and ulcers. They are mostly common in Kerala and Kanyakumari and found throughout India. It is commonly described to as wild jack and the fruit are edible to eat and wood are help to make furniture. The seed oil used by makes food by local people. According to Ayurveda records, it may relieve vata and pitta imbalances, anorexia, and burning sensations in the extremities. They are rich in source of alkaloids, proteins, carbohydrates, glycosides, saponins, phenolic compounds, flavonoids, and terpenoids, Lactones, Tannins, and Steroids. Their biological benefits include anti- apoptosis, anti-aging, anti-carcinogen, antiinflammatory, anti-atherosclerosis, and cardiovascular improvement. The antioxidant potential of medicinal plants with high phenolic content has been shown in numerous researches. Since plants contain flavonoids and phenolic acids, they are a natural source of antioxidants. They exhibit strong inhibition of tyrosinase and antioxidants. Oxyresveratrol is present in ethanolic wood extract and has neuroprotective, antiviral, and anticancer effects. It also inhibits cyclooxygenase. Since oxyresveratrol has greater antioxidant activity, less cytotoxicity, and a higher bioavailability than resveratrol, it is a promising dietary supplement, pharmaceutical, and cosmetic agent.

Keywords: Artocarpus hirsutus, Moraceae, Artocarpus, Pharmacology, Phytochemistry, Antioxidant, Anti-microbial, Anti-cancer.