Abstract

FORMULATION OF HERBAL SANITIZER FROM CAESALPINIA BONDUCELLA

Sarang Palaskar*, Divya Deshmukh, Shubham Kothalkar, Kamlesh Kadam and Dr. Hemant Gangurde

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Abstract

Medicinal plants are the main source of pharmaceuticals and healthcare products. In the present study, our goal was to investigate the phytoconstituents in the leaf extracts of Caesalpinia bonducella and their antimicrobial activity. The phytochemicals analysis of leaves powder of Caesalpinia bonducella was carried out by using extraction method. Caesalpinia bonducella leaves contain Terpenoids & Phenolics 4.490%, Alkaloids 0.885%, Q. Alkaloid & N-oxides 25.745 %, fats and waxes 8.850% and Fibers 60.050%. Antimicrobial studies showed that the above extracts had considerable activities against Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Klebsiella aerogenes, Aspergillus niger and Penicillium chrysogenum. The percentage of fats and waxes, terpenoids and phenolics, Q. Alkaloid & N-Oxides was observed good. Its beneficial effect on animals as well as human health may be derived from its antibacterial and antifungal properties to afford protection against various diseases. It might be an alternate to synthetic antibiotics available in the market.[1] Hand hygiene is of unconditional importance as it may be contaminated easily from direct contact with airborne micro-organism droplets from coughs and sneezes. To date, most of the effective hand sanitizer products are alcohol- based formulations containing 62%-95% of alcohol as it can denature the proteins of microbes and the ability to inactivate viruses. Caesalpinia bonducella leaves has significant antidiarrhoeal properties. The methanol extract and other three fractions of the C. bonducella leaves possess potent antibacterial activities along with moderate cytotoxicities that may lead to new drug development.[2]

Keywords: Caesalpinia bonducella, quaternary alkaloids, terpenoids and phenolic, phytochemical, anti-microbialactivity.