Abstract

A BRIEF REVIEW ON Α-AMYLASE INHIBITORY ACTIVITY OF PLANTS IN TREATMENT OF DIABETES MELLITUS

Mitesh A. Khaleshiya*, Morvi M. Raval, Chintankumar J. Tank, Dhaval R. Zala, Dhrutika J. Barad and Vishvajit N. Parmar

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Abstract

Due to postprandial glucose levels, alpha-amylase inhibitors have gained attention as possible therapeutic agents for the treatment of metabolic diseases like diabetes and obesity. This review examines the several plant species that exhibit alpha-amylase inhibitory characteristics. It also talks about how the phytochemical components in these plants may work in concert to increase their inhibitory efficacy against alpha-amylase enzymes. This review also explores the pharmacological importance of alpha-amylase inhibitors produced from plants, including how they control blood glucose levels and possible uses in diabetes prevention explaining thorough plant profile.

Keywords: Diabetes mellitus, Alpha-amylase activity, Role of metalloenzymes.