Abstract

CHROMATOGRAPHICAL AUTHENTICATION AND STANDARDIZATION OF UNANI HERBAL FORMULATION HABB-ESURANJAN

Asma Sattar Khan*, Shoeb Ahmed Ansari, Firoz Ahmad Ansari, Reesha Ahmed,Suryansh Kashyap and Ram Pratap Meena

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Abstract

The Unani system of medicine has a long history of usage for the treatment of various diseases. During and after the COVID period, people realized its significance and a rapid growth has been observed in the usage of Unani medicine. This rise has posed novel challenges for proper authentication, safety and efficacy of Unani medicines. Hence, adoption of appropriate methodology is necessary to evaluate the quality of herbal medicines for their safe consumption. The Unani poly-herbal formulation; Habb-e-Suranjan, widely used as an effective analgesic for all types Waj-al-Mafasil (Arthralgia), Irq-un-Nisa (Sciatica), Niqras (Gout), Falij (Paraplagia), Laqua (Facial Paralysis or Ball’s Palsay). The drug was studied through various standardization parameters such as organoleptic evaluation (color, odor and taste), physico-chemical evaluations (moisture content, total ash, acid insoluble ash, pH values, water and ethanol soluble extractive and volatile oil), with the chromatographic technique like HPTLC fingerprinting. The WHO quality control parameters such as heavy metals, aflatoxins, pesticide residues and microbial load were also carried out to check the presence of any hazardous substances in the formulation. The data produced in this study will lead to develop authentic pharmacopoeial standard of Habb-e-Suranjan which eventually leads to estimate the quality, safety and efficacy of the formulation.

Keywords: Authentication, physico-chemical analysis, quality control parameters and HPTLC fingerprinting.