Abstract

SYNERGISTIC EFFECTS ON IMMUNOMODULATION IN SYSTEMIC LUPUS ERYTHEMATOSUS (SLE): INTEGRATING AYURVEDIC AND CONVENTIONAL TREATMENTS – A REVIEW

Dr. Khushali S. Shroff and Dr. Abhaychandra S. Inamdar*

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Abstract

Systemic Lupus Erythematosus (SLE) presents a complex autoimmune landscape characterized by dysregulated immune responses, leading to chronic inflammation and potential multi-organ involvement. The management of SLE encompasses a multifaceted approach aimed at controlling symptoms, preventing flares, and minimizing organ damage. Immunomodulating therapies that are not immunosuppressive, are a more attractive therapeutic option, offering the opportunity to modify the aberrant immune responses in SLE and thus prevent inflammation and subsequent damage without the risks of infection and malignancy. This review outlines the immunologic actions of these drugs by identifying the potential synergies between Ayurvedic and conventional treatments, assessing whether their combination enhances therapeutic outcomes beyond individual modalities.

Keywords: SLE, Autoimmune conditions, Ayurveda, Rasayana, Immunomodulation.