Abstract

SYSTEMIC LUPUS ERYTHEMATOSUS PRESENTING WITH GUILLAIN–BARRE SYNDROME: A CASE REPORT

Dr. Anjum Ahamadi*, Dr. Meraj Fatima, Dr. Ayesha Ambereen, Dr. Ayesha Asif Ali, Dr. Syed Shoaib Hussain and Dr. Suhail Syed

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Abstract

We present a case of systemic lupus erythematosus (SLE) coexisting with Guillain–Barre syndrome (GBS), where GBS gradually progressed to SLE. A 32-year-old female with previously diagnosed SLE presented with symptoms suggestive of GBS, including leg pain, loss of balance, and lower extremity weakness. Prompt initiation of therapy for GBS and consideration of chronic inflammatory demyelinating polyneuropathy (CIDP) were crucial. This case underscores the significance of early diagnosis of autoimmune disorders to facilitate timely intervention and improve patient outcomes. Introduction: The co-occurrence of systemic lupus erythematosus (SLE) and Guillain–Barre syndrome (GBS) is rare. Here, we report a case where GBS preceded the manifestation of SLE, emphasizing the importance of vigilant monitoring and prompt intervention in autoimmune conditions. Case Presentation: We present a 32-year-old patient with SLE who presented with GBS. The patient came with progressively worsening neurological symptoms as the first manifestation. Leg pain, loss of balance, and lower extremity weakness were the reasons for her admission to the neurologic ward. The patient staarted the therapy based on the possibility of Guillain– Barre syndrome and chronic inflammatory demyelinating polyneuropathy (CIDP). Conclusion: This case highlights the significance of early recognition and management of autoimmune diseases. Timely intervention not only aids in controlling disease progression but also contributes to better prognostic outcomes. Data collection: All the Data was collected from the patient's case sheet and the hospital laboratory medicine database.

Keywords: Systemic Lupus Erythematosus, Guillain-Barre syndrome, chronic inflammatory demyelinating polyneuropathy, autoimmune disease.