Abstract

IN VITRO ANTIMICROBIAL ACTIVITY OF SOME PLANTS AGAINST HUMAN PATHOGENIC FUNGI

Saurabh Gupta* Reena Bhardwaj and Neha Patel

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Abstract

In traditional medicine of India, around 40% of herbal plants are used to treat diseases caused by pathogenic fungi. Medicinal plants are common in India; many plant species potentially useful for new pharmaceuticals are less studied. However, the antimicrobial properties of several medicinally important plants from various countries are still unknown. This paper aims to provide report on the antimicrobial activity of Datura mate and Butea monosperma medicinal plants used again Human pathogenic microbes as traditional medicine. A total of 8 fungal pathogens were isolated from various diseased samples of human body. Aspergillus niger (FCHP#05) was the most fungal sp. Isolated accounting for 43% followed by Aspergillus flavus (FCHP#06) 32%, Candida (FCHP#04) 26%, Tricophyton sp. (FCHP#02) 22%, Aspergillus fumigates (FCHP#07) 16%, Microsporum sp. (FCHP#01) 12%, Cladosporium sp. (FCHP#08) 11% and Epidermophyton sp (FCHP#03) 08%. Alcoholic leaves extract of Cassia fistula, Datura mate and Butea monosperma spp. was subjected to antifungal activity by agar well method and disk diffusion method. Maximum percentage inhibition was observed with 7 Days of incubation viz. Epidermophyton sp., Tricophyton sp., and minimum percentage inhibition was observed. Candida followed by Aspergillus niger by agar well and disk diffusion method.

Keywords: Antifungal activity, Plants, Human pathogenic fungi.