Abstract

RESEARCH ARTICLE ON FORMULATION OF TRANSDERMAL ANTIFUNGAL CREAM BY USING CASSIA FISTULA EXTRACT OF HERBAL PREPARATION

Prof. Tanuja M. Wankhede, Rushikesh N. Desale*, Shreya Dhandgwal, Khushi Deore, Jayent Changale and Naved Deshmukh

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Abstract

The purpose of the study was to produce herbal preparation of antifungal cream with a composition of the herb cassia fistula Linn for treating fungal skin infections. These creams belong to herbal medicinal cream which containing herbal antifungal drug. For treatment of skin infection caused by fungi belong to family Candida and Aspergillum spp. the formulation containing herbal antifungal drug which has broad spectrum of antifungal activity. When Transdermal drug delivery is one of the most prospective strategies for medication application through the skin, particularly the stratum conium, which features a horrible barrier to drug penetration, limiting topical and transdermal bioavailability. So skin penetration improvement techniques have been created to improve bioavailability and expand the range of medications, with topical and transdermal delivery being a potential option. The procedure is generally noninvasive, widely accepted by patients, and can be utilized to provide local delivery over a number of days. In which used a various types of chemical agent for enhancing penetration power of skin. Topical formulation (cream or gels) which play most important role. Because of several advantages it contains skin penetration enhancer which enhanced penetration power of cream which increased bioavailability. The purpose of this page is to provide a complete summary of the outcomes from scientific studies undertaken on antifungal activity of cassia fistula and skin penetration enhancer of synthetic or natural origin. Essential oils, fatty acids, terpenes, and polysaccharides. In transdermal cream.

Keywords: Cassia fistula, Antifungal infection, skin penetration enhancer, Essential oils, herbal cream.