Abstract

A REVIEW ON DENDRIMERS: THE NOVEL DRUG DELIVERY SYSTEM

Ghumare P. J.* and Basarkar G. D.

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Abstract

Dendrimers are a new way to send drugs that could be useful because they get around many of the problems with older methods. Dendrimers have been around for a while. This page talks about their past, what makes them unique, how they are made, and how they are used to deliver drugs. Some of the benefits of dendrimers are better drug solubility, controlled release, and less toxicity. They are defined by their high symmetry, surface polyvalency, and monodispersity. Medicines, genes, and imaging chemicals are just some of the restorative materials that can be contained by them. The physiological properties of dendrimer-drug conjugates are better and they work better than free medicines. A lot of different methods, like convergent and divergent growth approaches, are used in dendrimer synthesis to finetune their structure and features. Biodegradable dendrimers could also be used to deliver medications precisely and over a long period of time. Because they are flexible and easy to control, dendrimer structures can be used in many biological ways. These include treating cancer, delivering vaccines, and transfecting genes. Even though they show promise, problems with toxicity and building up synthesis processes still exist. Dendrimers haven't been used a lot in therapeutic settings yet, but that's starting to change as study and technology keep getting better.

Keywords: Dendrimers, Drug delivery, Nanomedicine, Synthesis, Biocompatibility, controlled release, Conjugates, Biomedical applications.