Abstract

HERBAL LOZENGES FOR APHTHOUS ULCERS

Lisha M. Moon*, Smita P. Mokle, Vaibhav E. Nimbone, Shaikh M. Zainuddin and Yuvraj Girbhane

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Abstract

Herbal lozenges have gained traction because it is a natural remedy for curing aphthous ulcersdue to their potency of therapeutic activity and fewer side effects as compared to synthetic medications. The purpose of this study is to formulate and evaluate herbal lozenges for treating aphthous ulcers using selected medicinal herbs that are known for their anti- inflammatory, antibacterial, and wound-healing properties. The formulation of herbal lozenges involves the isolation of herbal extracts, excipients, and flavoring agents to improve the stability, taste, and therapeutic efficiency of the lozenges. The herbal lozenges were prepared by using two methods i.e. by heat and congealing method and by using gelatin as a base. The lozenges were evaluated on the basis of their thickness, diameter, hardness, friability, weight variation, disintegration time, stability, antimicrobial activity and in-vitro dissolution. Further the evaluation includes sensory analysis i.e. taste, aroma and overall acceptability of herbal lozenges. Overall the formulation and evaluation of herbal lozengesfor aphthous ulcers showed promising results in terms of their physical characteristics, drug release profile and sensory attributes.

Keywords: Herbal lozenges, aphthous ulcers, anti-inflammatory, antibacterial, enhancement, therapeutic efficiency, Clove buds, Turmeric, Ginger, Honey.