Abstract

HPTLC CHARACTERISATION OF CAKRAMARDA BIJA - (SEED OF CASSIA TORA LINN.)

G. Sai Sireesha*, Renu Dixit and K.V.V. Bhaskara Reddy

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Abstract

Background: Cassia tora Linn. is commonly known as Foetid Cassia, a well-known Plant to treat Dadru Kushtha and several diseases explained in Ayurvedic texts is noted to be one of the principle ingredients on many of the formulations like Maharaja prasarini tailam, Trnatailam and Dadruvidravahana malhara, Pancanimbadi Curna etc. The drug is found to be a Laxative, Febrifuge and known to exhibit different Pharmacological activities. The Powder extract which is taken for the study must have authentication and scientific evaluation for the safety usage and application in Clinical trials for therapeutic efficacy. HPTLC method is the accurate and rapid screening technique for the evaluation of Phyto-Constituents present in Powder extract of the seed can be useful for the standardisation of the drug. An attempt is made to find the chemical constituents in the drug Cakramarda Bija (Cassia tora Linn.). The presence of bio active compounds in plants makes them Pharmacologically valuable due to qualitative and quantitative analysis and is essential as the constituents of the extracts identified will be useful in various diseases. Therefore, in the present study, the high performance thin layer chromatography (HPTLC) analysis of Cassia tora (Seed) was performed. The densitometric scans, Photo documentation and retention factor values were all recorded. The data given in this paper will provide the parameters required for the quality control of the drug and standardisation purposes.

Keywords: Densitometric scan, Cassia tora Linn., Cakramarda, HPTLC, Seed, Di ethyl ether, Toluene, Acetic acid, Rf Value.