Abstract

PHYTOCHEMICAL ANALYSIS AND ANTIMICROBIAL ACTIVITY OF LEAVES OF DALBERGIA SISSOO

Yathakula Vinaysree*, Ramya Madhiri, Charugundla Harini, Anwesha Pal and Battala Swapna

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Abstract

Nature, a vast repository of medicinal plants has played a pivotal role in shaping modern pharmaceuticals. Among these, Dalbergia sissoo stands out for its extensive use in traditional medicine globally. Dalbergia sissoo is also an herbal medicinal plant that belongs to the family Fabaceae (Leguminosae). This comprehensive review delves into the literature surrounding Dalbergia sissoo, elucidating its traditional applications, phytochemistry, and therapeutic uses. Various plant parts, from leaves to wood and bark, have found utility in treating diverse ailments, including gonorrhea and skin disorders. Research underscores the antimicrobial process of Dalbergia sissoo, showcasing potent antibacterial activity against both gram-positive and gramnegative bacteria. Notably effective against clinical isolates, the plant’s extracts present Potential Avenue for crafting antiseptic formulations targeting chronic bacterial infections. Despite its multifaceted benefits, Dalbergia sissoo has yet to be developed into a pharmaceutical drug. This underscores the need for systematic studies, including identification, cataloging, and documentation, to preserve and propagate traditional knowledge of herbal medicinal plants. Plant part extracts from Dalbergia sissoo are reported on anti-inflammatory, anti-termite, anti-diabetic, analgesic and antipyretic, antihelminthic, antioxidant, antimicrobial, antinociceptive, osteogenic, antispermatogenic, gastroprotective, neuroprotective, anti-molluscicidal, antilarvicidal, antiulcer, immunomodulatory, antibacterial activity Explorations into the plant’s antioxidant properties reveal potential in free radical scavenging and lipid peroxidation inhibition. In summary, Dalbergia sissoo emerges as a versatile medicinal plant with a rich history and promising pharmacological activities. Future research holds the key to unlocking its full therapeutic potential and seamlessly integrating it into modern healthcare practices.

Keywords: Dalbergia sissoo, Antimicrobial Activity, Lipid Peroxidation, Agar media, Methanol, Staphylococcus aureus, E.coli, and Candida Albicans.