Abstract

FORMULATION AND EVALUATION OF ACECLOFENAC – LYCOPENE TRANSEMULGEL

Hyndavi Narendran*, Swetha Koorapati , Lohita Mamidibathula

Abstract

Lycopene is a carotenoid present in tomatoes. It occurs in the human diet predominantly in tomatoes and tomato products Lycopene is well absorbed if applied topically because it is fat soluble and has relatively small molecules. This pigment acts as an antioxidant in the body, protecting cells against damage from the free radicals formed when body cells burn oxygen for energy. The present study highlights the formulation and evaluation of aceclofenac – lycopene emu gel .The gel was prepared by using carbapol 934, gel base and the aceclofenac drug was incorporated into the emulsion to produce transemulgel. The formulated transemulgel was evaluated for their rheological properties, drug content and diffusion studies. The transemugel has showed viscosity of 98cps, pH of 6.36 and good permeation capacity.

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