Abstract

ADVANCEMENTS IN TOPICAL GEL FORMULATIONS FOR DERMATOLOGICAL APPLICATIONS

Aman Thakur, Puneet Kumar, Supneet Kaur*, Evinka Barjataya and Naresh Singh Gill

.

Abstract

Although they're easier to apply and have superior precutaneous absorption, topical gels are growing in popularity. Gels are formulations that are semisolid, immobilized inside the void of a threedimensional network structure, and contain an external solvent phase. They can also be hydrophobic or hydrophilic. Comparing gel formulations to cream and ointments, the former offer superior stability and application properties. The primary route for topical drug delivery systems is the skin, which is one of the largest and easiest organs in the human body to access for topical administration. Topical gels are designed for application to the skin or specific mucosal surfaces in order to provide localized action, allow medication to penetrate through the skin, or provide emollient or protective properties. Other gel types-such as proniosomal gels, emulgels, bigels, and aerogels-for cutaneous medication administration have been reported in recent investigations. This review covers every detail pertaining to new methods of topical gel formulation, as well as the Advantages and categories of gel.

Keywords: Emulgel, Topical gel, Hydrogel, Rheology, Gel formulation, Polymers, Qbd.