Abstract

A REVIEW ON DIFFERENT FORMULATIONS OF BACLOFEN FOR SPASTICITY

Narendra Narayan Singh*, Vishal Singh, Shiv Jee Kashyap

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Abstract

Spasticity is a medical term that refers to a condition characterized by involuntary muscle stiffness, tightness, or spasms. It is often caused by damage to the central nervous system, particularly the brain or spinal cord. Conditions such as cerebral palsy, multiple sclerosis, stroke, and certain spinal cord injuries can lead to spasticity. In spasticity, the muscles affected by increased tone may become rigid, making movement difficult and causing discomfort. The increased muscle tone is a result of abnormal signaling from the nervous system, leading to exaggerated reflexes and muscle contractions. Physical therapy, medications, and sometimes surgical interventions are common approaches to managing spasticity and improving the affected individual's mobility and quality of life.

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