Abstract

AYURVEDIC APPROACH IN THE MANAGEMENT OF GLYCOGEN STORAGE DISORDER- A CASE STUDY

Dr. Nilam Mahadev Sambre*, Dr. Ravindra Ramchandra Rajpal and Dr. Deepak Khawale

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Abstract

Glycogen storage diseases are inherited metabolic disorders of glycogen metabolism. It is an autosomal recessive disorder. Inborn errors of metabolism result from the lack of level of specific enzymes that are needed to insufficient tile convert fat. Whenever glycogen is turned from glucose a different enzyme is needed in each step and when one of the enzymes becomes defective it fails to complete the step. These defects in the enzyme can lead to Glycogen storage disease. Type I GSD is a condition where there is a lack of glucose 6 phosphates enzyme it affects the liver, spleen, kidney, and small intestine. Common symptoms" are hypoglycemia, lactic acidosis, and Hepatosplenomegaly. Treatment of type I GSD is symptomatic. The patient experienced significant relief from all the symptoms. i.e., Hepatosplenomegaly, Abdominal distension, loss of appetite, Generalised weakness. Her efforts were made to manage this condition by the Ayurvedic medicine administration. A female child aged 6 years from Alandi, Pune, Maharashtra, has a known case of Glycogen storage disorder in the last 4.5 years. Through her physical, clinical, and anthropometric examinations, she was diagnosed with Case Glycogen storage disorder. The patient has complaints, of generalized weakness, distension of the abdomen, and anorexia. The patient was examined, there was a Hepatosplenomegaly and diagnosed as Yakritodara & Pleehodara & treated with Shamanoaushadi. Distension of abdomen reduced; generalized weakness reduced with increased appetite. The patient gave a remarkable improvement in symptoms. In this case study, we are going to throw light on GSD and its treatment through Ayurvedic medicine.

Keywords: Glycogen storage disease, Yakritodara, Pleehodara, Metabolic disorder, GSD.