Abstract

RESEARCH ARTICLE: FORMULATION AND EVALUATION OF FLOATING TABLET

Aishwarya Vijayrao Deshmukh*, Dr. S. R. Gawande and Dr. A. V. Chandewar

.

Abstract

Floating matrix tablets were developed to prolong gastric residence time and increase drug absorption further increasing the bioavailability. Various forms of gastro retentive drug delivery system, such as floating and non- floating. Floating tablets was formulated to increase gastric residence and there by improve its therapeutic efficacy. By using different polymers such as carbopol, guargum, HPMC K100, HPMCK4 etc. By using direct compression method. Formulated F1 to F10 batches tablets showed satisfactory results for various post compression evaluation parameters like thickness, hardness, weight variation, floating lag time, total floating time, content uniformity and invitro drug release. Formulation batches were perform in that all batches were passes to preformulation study and post formulation study was F6 batch are obtimise to passes all parameter’s.

Keywords: Floating Drug Delivery System, Floating tablets, GRDDS.