Abstract

FLOATING DRUG DELIVERY SYSTEM: AN OVERVIEW

Jaiswal Goutam, Gupta Ashish* and Darwhekar Gajanan

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Abstract

Floating drug delivery systems (FDDS) have a lower bulk density than gastric fluids, consequently they float in the stomach for longer decades of time without altering the gastric emptying rate. The medicine is released gradually and at a controlled pace from the system while it is floating on the stomach contents. The residual approach in the stomach is emptied once the medicine is released. As a consequence, the Gastric Residence Time (GRT) is enhanced, and differences in plasma drug concentration are better controlled. The system must have enough structure to formulate a cohesive gel barrier and disintegrate gradually enough to act as a drug reservoir while maintaining an overall specific gravity lower than that of stomach contents. The techniques used to create both non-effervescent and effervescent floating tablets based on buoyancy mechanisms in order to expand FDDS. Using the previously effective. Thus, it is possible to provide medications with a limited window of therapeutic action. The goal of our review paper is to provide thorough information on the pharmaceutical foundations of FDDS's design, classification, preparation factors that affect FDDS, benefits, uses, disadvantages, and potential future applications.

Keywords: Gastroretentive System, Gastric emptying rate, HBS and Floating Drug Delivery System.