Abstract

AN OVERVIEW ON THE ANALYSIS OF THE FLOATING DRUG DELIVERY SYSTEM

Ravi Kumar Gupta*, Prabhudatta Panda and Dhiraj Kumar

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Abstract

The idea behind the creation of a unique delivery method was to address some of the shortcomings of traditional dosage forms and to address issues with the physicochemical characteristics of drug molecules and formulation development. One potential delivery method is the controlled release floating medication delivery device, medicines that localize release in the stomach, have a restricted window of absorption, are sparingly soluble and insoluble, or have poor absorption in the colon. A gastroretentive drug delivery system, which offers continuously regulated administration of medications that are sparingly soluble at the absorption site, is what is referred to as a floating drug delivery system. The comprehensive situation pertaining to the floating drug delivery system is covered in this review, along with its benefits over the traditional drug delivery system and its drawbacks, which are useful for formulating dosage forms. Different kinds of methods used for creation of this dose format. Review of the effervescent floating medication delivery system's formulation and assessment methods was the main emphasis. Compiling the work being done on this delivery method is the aim of this thorough assessment. They cover the several aspects that impact stomach Retention and Offer useful knowledge on the formulation part of achieving it.

Keywords: Gastroretentive drug delivery system, Absorption, Stomach retention, effervescent.