Abstract

AN OVERVIEW: TRANSDERMAL PATCH FOR TOPICAL DRUG DELIVERY SYSTEM FOR ANTIFUNGAL EFFECT

Rajat Rohilla*, Anshu and Jiyaulhak

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Abstract

Transdermal drug delivery system was 1st introduced more than 20 years ago. This system is type of traditional drug delivery system in which drug under goes to the systemic circulation through the protective barrier i.e. skin. Skin is a major target and barrier for topical and transdermal drug delivery, but the low diffusion rate across the stratum corneum is a major hindrance. Various methods have been conducted to improve drug permeation rate temporarily via skin, such as by help of elastic vesicles or skin enhancers. Vesicular systems like ethosomes, are controversial methods for transdermal drug delivery due to their higher penetration rate through the skin due to their ethanolic content. Nanosuspension are colloidal dispersion of nanosized drug particle stabilized by surfactant particle of nanosuspension is less than 1mm to 200-600mm.

Keywords: Anti-fungal, Topical route, Transdermal patch, Skin.