Abstract

DRUG UTILIZATION AND EVALUATION OF ANTI-EPILEPTIC DRUGS IN SEIZURES

Krishna Kuruva*, Sravani Ganji and Dr. D. Venkata Ramana M. Pharm; Ph.D

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Abstract

Background: Antiepileptic drugs are available to treat seizures and epilepsy. The main purpose of the study is to evaluate the utilization and prescribing pattern of antiepileptic drugs. Methods: Case reports of 126 seizures patients with anti-epileptic drugs were collected in the neurology department of sunshine hospital, Secunderabad. The collection of information regarding the initial treatment prescribed for patients with seizures and its prescribing pattern was studied, analyzed, and evaluated. Results: Among the 126 the percentage of male (58.7%) and females (41.3%). Most of the patients from the department of neurology (52%). Based on the anti-epileptic drugs in seizures, levetiracetam was the mostly employed medications (87%) in patients and lacosamide was the mostly employed medication in patients with (14.2%). Mostly employed route of administration of medication was the intravenous route. Conclusion: The review uncovered that the pervasiveness of seizures was more among males at 58.7% when contrasted with females at 41.3%. The commonness of seizures was viewed as more around the age gathering of 41-50 years. It was seen that the majority of the patients are having a low recurrence between the seizure episodes and are influencing their personal satisfaction. Mono treatment hostile to epileptic medications was usually recommended among the review members. The most recommended enemy of epileptic medication was found to be levetiracetam at the level for 110 patients (87.3%) trailed by Lacosamide for 18 patients, Librium for 14 patients, and brivaracetam for 13 patients.

Keywords: Drug utilization and evaluation, Anti-epileptic drugs and rational uses.