Abstract

PHYSICOCHEMICAL AND BIOLOGICAL EVALUATION OF RAKTASHODHAKARISHTA

Sajeena C. H.*, Arya V., Ashika Sanam N. M., Fathima P., Mohamed Anas, Celestin Baboo R. V. and Sirajudheen M. K.

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Abstract

The most well-known traditional Indian medical practices, such as Ayurveda, Sidha, Unani, and Homeopathy are gaining popularity across the globe. In the ayurvedic medical system, Arista is a self-made herbal mixture. Raktashodhakarishta is a classic Ayurvedic composition used for the skin diseases and blood purification. The aim of the present study is to identify the chemical components present in the Arista, such as alkaloids, phenolic and tannins, flavonoids, glycosides, carbohydrates, steroids, saponins, terpenoids and protein and amino acids. And to determine how they related to the antiinflammatory, anti-bacterial, and anti-oxidant qualities. Also, the present study aims to determine the physicochemical properties like alcohol content, ash values, extractive values, moisture content, viscosity, and specific gravity. The anti-bacterial activity was evaluated by gram positive and gram-negative bacteria by agar plate method. The DPPH scavenging assay was used to assess the anti-oxidant activity. And anti-inflammatory property of the Arista was evaluated by the protein denaturation method by egg’s albumin with using standard as Diclofenac Sodium.

Keywords: Raktashodhakarishta, anti-inflammatory, anti-oxidant, anti-bacterial activity, DPPH.