Abstract

A REVIEW: INTRODUCTION OF LUFFA CYLINDRICAL WITH PHARMACOLOGICAL ACTION

Praduman Kumar Nagar*, M. K. Gupta and Shreya Singh

Abstract

Luffa cylindrica is an important for the treatment of various type of diseases. Also it is an edible vegetable in India also other country. Luffa Cylindrica is a used for the Treatment of Nasal Swelling and Sinus Problems. Gourds produce long, cylindrical fruits, 10–40 cm in length and 6–10 cm in diameter. It also helps to remove the buildup of dead skin cells accumulated over the surface of your skin. Intraperitoneal administration of water decoction of Sigualuo inhibited carrageenan induced plantar edema in rats. It has carried out phytochemical screening and Anti-inflammatory, Bronchodilator. The preliminary phytochemical screening of Luffa cylindrica revealed that the plant contained anthocyanins, glycosides, flavonoids, triterpenoid, cardiac glycosides, saponins, carbohydrates, proteins, alkaloids, and tannins. The seeds of the plant contained crude protein 33.55±1.01 %, fiber 6.47±0 %, fat 22.17±0.28 %, carbohydrate 29.51±1.83 %. evaluated methanolic extract of Luffa cylindrica fruits for its antihyperglycemic potential in Swiss albino mice. Antihyperglycemic activity was evaluated through oral glucose tolerance test (OGTT) in glucose-loaded mice. In antihyperglycemic activity tests conducted with glucose-loaded Swiss albino mice, methanolic extract of fruits significantly and dose-dependently reduced blood glucose concentrations. Oral administration of the petroleum ether fraction of the ethanol extracts of fruits, leaves and stems potentiated the cytophagic action and acid phosphatase activity of peritoneal macrophages in mice.

Keywords: Antihyperglycemic activity was evaluated through oral glucose tolerance test (OGTT) in glucose-loaded mice.