Abstract

EVALUATION OF ANTIBACTERIAL ACTIVITY OF BAUHINIA VARIEGATE LEAF EXTRACT USING DISK DIFFUSION METHOD AGAINST SOME HUMAN PATHOGENIC BACTERIA’S

Purva Jain, Priyanka Pandey* and Wasim Raja

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Abstract

Microbial resistance to antibiotics is highly increasing during the three last decades. Evaluation of natural products to access new and effective antimicrobial agents is one of the scientific strategies to combat drug-resistant pathogens. With this perspective, leaf extracts of Bauhinia vareigata which had documented uses in traditional medicine, Bauhinia vareigata leaf extract tested against some Gram-negative and Gram-positive bacteria such as Bacillus subtilis, Bacillus cereus, Bacillus frimicutes, Escherichia coli, Entrobacter, Klebsiella, Escherichia coli. The antimicrobial activities were evaluated using agar disc diffusion method. The results indicated that the antimicrobial of Bauhinia vareigata Linn inhibit the growth of microorganism’s as dose dependently manner. They appear results confirm that the antibacterial activity of Bauhinia vareigata leaf extract in present test system. It is concluded that this plant can be indispensible source for secondary metabolites.

Keywords: Bauhinia vareigata, methanolic, Pathogenic Bacteria, E. Coli, Leaf, antibiotics.