Abstract

HAEMATINIC ACTIVITY OF PULI ILAI CHOORANAM IN PHENYLHYDRAZINE INDUCED ANEMIC RATS

Arunmozhi P *, Gnanavel IS, Sivasaravanan K.S, Velpandian V

Abstract

Iron deficiency is the most common and widespread nutritional disorder in the world. Bio-availability is a major criteria in taking synthetic haematinic preparations, whereas in Siddha system of medicine, easy availability, greater bioavailability of haematinic drugs which can be achieved through the treasured natural medicines. One such medicine is �Puli Ilai Chooranam� Tamarindus indica Linn. The haematinic activity of Puli Ilai Chooranam was studied in Phenylhydrazine induced anaemic rats. Anaemia was induced by an oral administration of Phenylhydrazine for a period of 7 days. The Puli Ilai Chooranam was administered at the various dose levels of 100mg/kg, 200mg/kg and 400mg/kg orally to the animals for 14 days. Hb concentration, RBC count, PCV, MCH, MCHC were analysed as indices of anaemia. Phenylhydrazine significantly decrease the haematological parameters. After 14 days of treatment with trial drug Puli Ilai Chooranam at the dose level of 400 mg significantly reverse the above parameters and turn towards the normal value. This result supports the traditional use of Puli Ilai Chooranam in the treatment of anaemia.

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