Abstract

CLINICOPATHOLOGICAL EVALUATION OF GLEASON SCORE AND GRADING GROUP IN PROSTATIC ADENOCARCINOMA IN BASRAH CITY (2019_2023) SCIENTIFIC COUNCIL OF THE ARAB BOARD OF ANATOMIC PATHOLOGY

Haneen Abdulameer Ahmed* and Sawsan Salih Al-Haroon

Abstract

Introduction: One of the most common types of cancer in males worldwide and a leading cause of cancer-related mortality is prostatic cancer. The diagnosis and aggressiveness of prostatic adenocarcinoma is based on two scoring systems, namely the Gleason score system and the grade group system both of them being included in the pathology report. The most widely used grading scheme for prostatic cancer is the Gleason system. Aim: To estimate the incidence of the Gleason score and grade group in prostatic adenocarcinoma and assess the association of them with the clinicopathological parameters: age and perineural invasion. Methodology: A total number of 210 cases were collected from governmental and private histopathologic laboratories in Basra city, the study period was conducted from beginning of January 2019 to the end of December 2023. Results: Among Two hundred and ten cases of prostatic adenocarcinoma, the most frequent Gleason score was 8 and 7 and the most frequent grade group-4. There was a significant statistical association between Gleason score and age group, also between Gleason scores, grade group and the existence of perineural invasion. Conclusion: The most frequent Gleason score was 8 (32.4%) and 7 (30.0 %), and the most grade group was group- 4 (31.9%). There was a significant association between Gleason score and grade group with ages and perineural invasion.

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