Abstract

COMPARATIVE PHARAMACEUTICO-ANALYTICAL STUDY OF MANDOOR BHASMA, SWARNAMAKSHIK BHASMA AND MANDOOR-MAKSHIK BHASMA

Dr. Nishant Ingle*, Dr. Satwashil Desai and Dr. Jayashree Kolhe

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Abstract

Background: Rasashastra, a unique branch of Ayurveda, focuses on the use of metals, minerals, and gemstones in medicinal formulations. This approach has yielded valuable contributions, including Bhasmas – processed metallic or mineral powders with enhanced bioavailability and therapeutic efficacy. Mandura Bhasma (iron oxide) and Swarna Makshik Bhasma (a compound of copper, iron, and sulfur) are wellestablished Bhasmas in Ayurvedic medicine, each known for its hematinic (blood-purifying) properties and applications in managing anemia. Traditionally, these Bhasmas have been used both individually and in combination. The therapeutic benefits of both Mandura Bhasma and Swarna Makshik Bhasma as individual agents are documented. Combining these Bhasmas extemporaneously (mixing separately prepared powders) is a common practice in Ayurvedic medicine. Rasatantrasaar Siddhaprayog Sangraha" introduces a unique formulation – Mandurmakshik Bhasma (MMBCP) – where the processing (marana) involves combining pre-purified Mandura and Swarna Makshik Bhasma. No work was done on this combination so study was undertaken, Aims of the Study: To study the comparative pharamaceutico analytical study of mandoor bhasma (MB), swarnamakshik bhasma(SB) and mandoor-makshik bhasma” Objectives. 1. Shodhana and marana of Mandoor as per classical reference mentioned in samhitas. 2. Shodhana and marana of Swarnamakshik as per classical reference mentioned in samhitas. 3. Marana of shuddha mandoormakshik as per classical reference mentioned in samhitas. 4. Analytical study of Mandoor Bhasma (MB), Swaramakshik Bhasma (SB), Combination of separately prepared Mandoor Bhasma and Swarnamaskshik Bhasma.(MMBSP), Combinely prepared Mandoor-Makshik Bhasma (MMBCP). Methodology: Shodhana and Marana of Mandoor Bhasma, Swaramakshik Bhasma, and Combinely prepared Mandoor-Makshik Bhasma were done as per classics. Results: After 32 putas, 5 putas Mandoor bhasma and mandura makshika bhasama passed all the Bhasma pariksha is which ash value is more which shows its inorganic nature and mandurmakshik is highly rich in iron oxide. Conclusion: The study confirms that the combined processing method (MMBCP) for Mandoor- Makshik Bhasma is more efficient (5 putas vs 30 putas) and cost-effective while retaining the properties of both original Bhasmas. Analysis shows all four Bhasmas in all are rich in iron oxide (Fe2O3>50%).

Keywords: The therapeutic benefits of both Mandura Bhasma and Swarna Makshik Bhasma as individual agents are documented.