Abstract

MICROBIAL INFECTION AND IL-6 URINE LEVELS FOR PREGNANT WOMEN IN THI-QAR PROVINCE

Hind M. Mousa* and Maytham T. Qasim

Abstract

Urinary tract infection is a common health problem, affecting millions of women especially pregnant women each year. The present study aimed to shed light on microbial infection and IL-6 urine levels proinflammotory cytokine in pregnant women. Urine samples from 70 pregnant women and 20 urine samples from non- pregnant women with urinary tract infection as a (control) were included in this study. Urinary tract infections were studied for all groups by culturing urine samples using specific culture media. The incidence ratio of positive urine culture in pregnant women was 52 (74.3 %) while 18(25.7 %) was the incidence of negative urine culture. The frequency of the different microorganisms causing UTI in patient groups were studied, in which Gram-negative, particularly Escherichia coli showed the highest incidence among them (28.9%) . Also, the age group 20-29 years had the highest incidence of infection (82.8 %), and the urine levels of IL-6 were estimated by ELISA , the results showed significant different in IL-6 mean levels between trimester pregnancy groups and control group (p ≤0.01). Results indicated microbial infection was high in pregnant women of Thi-qar province, so urine microbial screening should be done in routine checkups for pregnant women.

Keywords: UTI, IL-6, pregnant women.