Abstract

PHARMACOLOGICAL INVESTIGATIONS OF FICUS LONGIFOLIA SABRE TREE

Madhur Kant*, Rakesh Kumar Meel, Bhanu P. S. Sagar and Amrita Singh

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Abstract

The goal of this research investigation was to conduct pharmacological research on Ficus longifolia for a number of different pharmacological studies. Flavanoids, steroids, terpenes, phenolics, glycosides, alkaloids, amino acids, and reducing sugars were found to be phytoconstituents in portions of the sabre tree. EELFL, EEAPFL, and EERFL had a very large safety margin and were categorised as non-toxic constituents. Significant anti-hepatotoxic action was obtained by EELFL, however it was smaller than that of normal silymarin. EELFL was found to reduce thiopentone sodium-induced sleeping time compared to CCl4 treatment. Compared to EEAPFL and EERFL, EELFL produced better action and reduced blood glucose. EELFL also markedly reduced blood glucose. Serum cholesterol levels were reduced with EETOL therapy (hypolipidemic / hypocholesterolemic action). It was therapeutic when EELFL raised the HDL level in the treated animals. LDL and VLDL levels were reduced with EELFL (therapeutically beneficial). It is suggested that more study be done to identify and define the pharmacologically active components of the Ficus longifolia extracts EELFL, EEAPFL, and EERFL.

Keywords: Ethanolic extract of leaves of Ficus longifolia (EELFL), ethanolic extract of aerial parts of Ficus longifolia (EEAPFL), and ethanolic extract of roots of Ficus longifolia (EERFL).