Abstract

EVALUATION OF PROPHYLACTIC ANTIBIOTIC USE AND INCIDENCE OF SURGICAL SITE INFECTION IN SURGICAL WARD OF A TERTIARY CARE HOSPITAL: AN OBSERVATIONAL STUDY

Dr. Jash Rakesh Pandya*, Dr. Akshaya Hitesh Patel, Dr. Pushti Jigneshbhai Desai, Dr. Krupa Prasannakumar Patel, Dr. Dharmendra Singh Rajput and Dr. Parth Prajapati

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Abstract

Introduction: Surgical Site Infection (SSI) is the third most common hospital acquired infection which accounts for 38% of all nosocomial infections. Appropriate use of Surgical Antibiotic Prophylaxis is an effective measure for the prevention of surgical site infection. Objectives: To evaluate the utilization of pre- and post-operative antibiotics in surgical ward, to assess the incidence of SSI, to evaluate drug use as per WHO core drug prescribing indicators, to evaluate rational use of antimicrobials according to Kunin’s criteria. Methodology: It is an observational study conducted in a tertiary care hospital involving 250 patients admitted in the surgical ward. All the relevant information needed for the study is collected from patient’s case sheet, file and by interviewing the patient. Statistical analysis: All the collected data is subjected to statistical analysis using MS Excel Windows and presented as number, percentage, mean with standard deviation wherever appropriate. Chi-square test and paired ttest is performed using Prism software. Results: Majority of the surgeries are associated with Clean-Contaminated surgical wound (54.76%). The commonly prescribed antibiotics in the surgical ward are Cefoperazone + Sulbactam (57.00%), Amikacin (14.50%) and Metronidazole (16.28%). The incidence of SSI was found to be 0.08%. 77.34% of antibiotics are prescribed appropriately according to Kunin’s criteria. Conclusion: Cephalosporin is the most commonly prescribed class of antibiotics in the present study. It can be concluded from the study that 60.73% of drugs are prescribed from NLEM. The incidence rate of SSI is minimal in the present study.

Keywords: Surgical Site Infection, Surgical Antibiotic Prophylaxis, Pre-operative, Postoperative.