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WJPR

World Journal of Pharmaceutical Research

( An ISO 9001:2015 Certified International Journal )

An International Peer Reviewed Journal for Pharmaceutical and Medical Research and Technology

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Abstract

ACTIVITY OF MITRACARPUS SCABER ON ENTEROCOCCUS FAECALIS

OKOU Obou Constantin*, ACKAH Jacques Auguste Alfred Bognan, ANGAMAN Djédoux Maxime, DJAMAN Allico Joseph

Abstract

In order to ascertain the antibacterial activity of Mitracarpus scaber (Rubiaceae), we tested five different extracts (aqueous extract, ethanolic extract 70%, insoluble residue in ethanol 70%, ethanolic extract 100% and butanolic extract) obtained from this plant on the in vitro growth of Enterococcus faecalis in Mueller-Hinton broth and Mueller-Hinton naehrboden agar. The results showed that all extracts were actives. Among those, the butanolic extract showed the highest bactericidal activity, with those values: MIC = 12,5 mg/ml, MBC = 1,56 mg/ml et IC50 = 0,06 mg/ml.

Keywords: Bactericidal, extracts, Enterococcus faecalis, in vitro, Mitracarpus scaber.

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