Abstract

‘’FORMULATION, EVALUATION AND PHARMACOLOGICAL PROPERTIES OF SHIAL KATA.’’

Amol G. Jadhao*, Sakshi G. Kambe, Shweta G. Takle, Akanksha C. Jadhao, Vaishnavi V. Chaudhari and Jayshri B. Sanap

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Abstract

Argemone mexicana is an indigenous herb commonly known as Prickly poppy. It belongs to the family Papaveraceae. Papaveraceae family is known to have CNS depressant activity, so A. mexicana was evaluated for CNS activities. It grows as weed in almost all part of India. It‟s potential as a medicinal plant has been practiced traditionally and been prescribed as medicines by Ayurvedic, Unani, Siddha and Homeopathic practices since several years. It is a wellknown weed in the agricultural and waste lands. Argemone mexicana is the source of a diverse kind of chemical constituents, alkaloids being most abundant. The plant consists of alkaloids, flavonoids, terpenoids, long-chain aliphatic alcohol, amino acids, carboxylic acid. It is reported to have antimicrobial Activity, wound healing property, larvicidal and, allelopathic potential, anti-malarial, antibacterial and antifungal, anti-cancer, anti-HIV and neuro-pharmacological activity. Analgesic and anti inflammatory studies of the ethanol extract of the roots of A. mexicana were studied in mice and rats respectively. Beyond pharmaceutical efficacies, certain plant parts also show toxic effects as well. Argemone Mexicana oil adulteration poses a serious threat to human health and should be checked by appropriate regulatory measures. Chemical investigations of this plant have revealed the presence of alkaloids, amino acids, phenolics and fatty acids. A. mexicana has shown promise as an effective bio-control agent. In light of these medicinal properties, this plant can be represented as a valuable source of medicinal compound. Argemone mexicana is a plant with evidence of traditional use for skin ailments including infection, psoriasis and cancer.

Keywords: Shial Kata, Protein, Non-Edible oil, Argemone Seed, Argemone Mexicana and Pale yellow.