Abstract

COMPREHENSIVE INSIGHTS INTO OLEOGELS

Nejina V. Hussain*, Dr. K. Premaletha, Anjana Lekshmi S. S., Dr. Vipin K. V., Abhanya Surendran and Dr. Ann Rose Augusthy

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Abstract

In recent years, oleogels have emerged as crucial entities in the pharmaceutical, cosmetics, and food industries, owing to their unique properties and versatile applications. Oleogels are non-crystalline, thermoreversible matrices wherein solid components, known as oleogelators immobilize vegetable oils. This review explores the fundamental aspects of oleogels, including their preparation, characteristics, and role as effective drug delivery systems. Compared to conventional gels, oleogels offer enhanced stability against moisture and microbial growth, making them favorable for pharmaceutical formulations. Their rheological properties facilitate the controlled and sustained release of active pharmaceutical ingredients (API) across various routes of administration such as topical, transdermal, oral, and ocular applications. Moreover, oleogels exhibit good biocompatibility and biodegradability, further supporting their safety and efficacy in therapeutic use. This article summarizes the key points regarding oleogels, highlighting their composition, benefits, and applications across different industries, focusing on pharmaceuticals.

Keywords: Oleogel, Oleogelator, Vegetable oil.