Abstract

TUBERCULOSIS CURE BY ISONIAZID: THE REVIEW PAPER

Varsha Yuvraj Kapgate* and Upadesh B. Lade

.

Abstract

Isoniazid is the most important heterocyclic moiety in organic and medicinal chemistry due to the existence of a reactive site in the molecule, which allows for its application in a variety of sectors. Isoniazid is the most important firstline medication for tuberculosis. Isoniazid’s unique molecular structure makes it an ideal candidate for drug creation. Antitubercular medicines are currently used, however they can be h azardous and require prolonged treatment. Researchers have developed novel med ications and mimics of existing treatments for tuberculosis. Newer analogues with substantial antitubercular action and few side effects have been developed. They are effective against multidrug resistant mycobacterium and can also be used in pati ents with HIV/AIDS.

Keywords: Tuberculosis, Isoniazid, Hepatotoxicity, Resistance, Mycolic acid.