Abstract

DENDRIMER-BASED NANOCARRIERS: A REVOLUTIONARY APPROACH IN CANCER THERAPY

Seema Vanave*, Kajal Sonawale, Rohini Kale, Payal Doble, Vishal Rasve

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Abstract

Cancer, a deadly disease, has experienced a transformative shift in treatment approaches with the integration of nanotechnology into medicine and diagnostics. Among the various nanocarriers, dendrimers have emerged as a promising tool for cancer therapy, including chemotherapy, gene therapy, and drug delivery. These unique supramolecular dendritic polymers offer several advantages, such as improved solubility and bioavailability, making them highly effective in delivering therapeutic agents. Despite significant advancements, one of the major challenges in cancer treatment remains the development of multidrug resistance to chemotherapeutic agents. However, dendrimers, with their three-dimensional, hyperbranched, globular nanostructures, hold great potential to overcome this hurdle by enhancing drug delivery and therapeutic efficacy.

Keywords: Cancer, Dendrimers, Nanocarrier, Theragnostic, Cancer Therapy, PAMAM, Drug Delivery etc.