Abstract

EFFICACY OF AMRITADI CHURNA IN AMAVATA W.S.R. TO RHEUMATOID ARTHRITIS: A CLINICAL STUDY

Dr. Govind Prasad Gupta*, Dr. Brahmanand Sharma and Dr. Avadhesh Shandilya

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Abstract

Introduction: The thesis delves into the therapeutic efficacy of Amritadi Churna, a formulation from Ayurvedic text Bhavaprakasha, in managing rheumatoid arthritis (RA). The study explores the historical context of RA, its etiology, and the challenges posed by its chronic nature. Drawing parallels between Amavata in Ayurveda and modern rheumatoid arthritis, the thesis emphasizes the need for effective treatments given the limitations of current interventions. Literary Retrospection: The conceptual part has been divided into two chapters i.e. Ayurvedic and Modern retrospection which contains glimpses of the Historical aspect of Amavata and the review of the previous works in ayurveda along with general description of Amavata, concept of Ama, Vata in Amavata, Nidana, Purvarupa, Rupa, Samprapti, Classification, Upadrava, Sapeksha Nidana, Upshayanupshaya, Sadhayasadhayata and Chikitsa Sidhanta along with a revie of modern medicine on Rheumatoid Arthritis and its differential diagnosis. Drug Review: It includes the review of drugs in Amritadi Churna (The trial Drug). It includes the reasoning’s behind selection of the drugs under trial, a general description of the ingredients from Ayurvedic point of view. Also selction of plant and preparation of trial drug is also included. Methodology: The research involves a detailed clinical study with 90 volunteer patients from the OPD/IPD wing of the P.G. Department of Kayachikitsa, University College of Ayurveda, Dr. S. R. Rajasthan Ayurveda University, Jodhpur, Rajasthan. Diagnosis is based on both Ayurvedic and modern criteria, including the American Rheumatism Association guidelines. A randomized group is administered Amritadi Churna for 60 days, and the patients' general characteristics, socio-demographic factors, and disease parameters are meticulously documented. The study meticulously evaluates the effects of Amritadi Churna on pain, swelling, stiffness, Angamarda, Aruchi, Trishna, Alasya, Gaurava, Jwara, Apaka, and Shoonta, along with subjective relief percentages. The research extends to objective parameters such as hemoglobin levels, total leukocyte count, differential leukocyte count, Creactive protein, erythrocyte sedimentation rate, fasting blood sugar, and RA factor. Results and Conclusion: The thesis concludes with a holistic assessment of the therapy's overall efficacy, considering both subjective and objective parameters. It acknowledges the significant relief in subjective symptoms and improvements in laboratory findings, while also highlighting areas where the therapeutic impact may be more modest. The importance of ongoing research and potential adjustments to enhance efficacy are emphasized for future studies.

Keywords: Diagnosis is based on both Ayurvedic and modern criteria, including the American Rheumatism Association guidelines.