Abstract

ANALYSIS OF VITIS VINIFERA (RESVERATROL) AS A LEUKOCYTE PROTECTOR IN BREAST NEOPLASM USING QUANTUM CHEMISTRY

Darcy Sofia Galindo-Sosa, Héctor Medina-Cruz, Jorge Zompantzi-Texis and *PhD. Manuel González Pérez

Abstract

Resveratrol (RVT) has been studied for several therapeutic properties, including its anticoagulant, antiarthritic, antineurotic, immunomodulatory, estrogen-like, antiaging agent, anticancer periodic, and carcinogenic activators, phase I and phase II inhibitors, cisplatin-resistant and sensitive tumor cells, and potent inducer of apoptosis. Breast neoplasia or breast cancer is a malignant tumor that originates in the cells of the breast. A malignant tumor is a group of cells that grow disorderly and independently, which tends to invade the surrounding tissues and distant organs (metastasis). This research used quantum chemistry to analyze Vitis vinifera (RVT) as a leukocyte protector in breast neoplasia. Quantum calculations were carried out with the semiempirical quantum simulator hyperchem. The beneficial effects of Vitis vinifera (RVT) were found in a slight reduction of erythrocytes in the chemotherapy of female patients in clinical cases. In other results not foreseen in the objective, it was found that RVT presents strong oxidation both to pure and sequenced AAs in any protein.

Keywords: Vitis vinifera, resveratrol, leukocytes, breast cancer, quantum chemistry.